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Marbofloxacin achieves high concentration in pig tonsils according to a dose dependent fashion
Vilalta Sans, Carles
Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicologia; Fraile Sauce, Lorenzo José
The penetration of marbofloxacin into tonsils was assessed in fattening pigs. Two different dosages were used to treat the animals: 2 mg/kg b.w. every 24 hours during 3 days (P1 group) and 4 mg/kg b.w. every 48 hours two times (P2 group. A ratio between the mean tonsillar concentration of marbofloxacin for both doses 24 hours after the last administration (0.5 and 0.7 µgr/mL) and its MIC90 for APP (0.03 µgr/mL) was calculated. These Ratio values were 16.6 and 23.3 for P1 and P2 group.
2011-05-04
615 - Farmacologia. Terapèutica. Toxicologia. Radiologia
Porcs -- Malalties -- Tractament
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